Predictive factors over time of health-related quality of life in COPD patients

Vista sencilla de ítem
dc.contributor.authorEsteban González, Cristóbal
dc.contributor.authorArostegui Madariaga, Inmaculada
dc.contributor.authorAramburu Ojembarrena, Amaia
dc.contributor.authorMoraza, Javier
dc.contributor.authorNájera Zuloaga, Josu
dc.contributor.author Aburto Barrenechea, Myriam
dc.contributor.author Aizpiri Rivero, Susana
dc.contributor.authorChasco, Leyre
dc.contributor.authorQuintana, José María
dc.date.accessioned2025-06-09T10:39:57Z
dc.date.available2025-06-09T10:39:57Z
dc.date.issued2020-06-05
dc.date.updated2025-06-09T10:39:57Z
dc.description.abstractBACKGROUND: Health-related quality of life (HRQoL) should be seen as a tool that provides an overall view of the general clinical condition of a COPD patient. The aims of this study were to identify variables associated with HRQoL and whether they continue to have an influence in the medium term, during follow-up. METHODS: Overall, 543 patients with COPD were included in this prospective observational longitudinal study. At all four visits during a 5-year follow-up, the patients completed the Saint George's Respiratory Questionnaire (SGRQ), pulmonary function tests, the 6-min walk test (6MWT), and a physical activity (PA) questionnaire, among others measurements. Data on hospitalization for COPD exacerbations and comorbidities were retrieved from the personal electronic clinical record of each patient at every visit. RESULTS: The best fit to the data of the cohort was obtained with a beta-binomial distribution. The following variables were related over time to SGRQ components: age, inhaled medication, smoking habit, forced expiratory volume in one second, handgrip strength, 6MWT distance, body mass index, residual volume, diffusing capacity of the lung for carbon monoxide, PA (depending on level, 13 to 35% better HRQoL, in activity and impacts components), and hospitalizations (5 to 45% poorer HRQoL, depending on the component). CONCLUSIONS: Among COPD patients, HRQoL was associated with the same variables throughout the study period (5-year follow-up), and the variables with the strongest influence were PA and hospitalizations.en
dc.description.sponsorshipThis work was supported by the Spanish Health Resarch Fund (FIS grant number PI020510), and by funding from the Departamento de Sanidad del Gobierno Vasco [grant number 200111002], Ministerio de Economía y Competitividad del Gobierno de España (MTM2016–74931-P), and Departamento de Educación, Política Lingüística y Cultura del Gobierno Vasco (IT1294–19)en
dc.identifier.citationEsteban, C., Arostegui, I., Aramburu, A., Moraza, J., Najera-Zuloaga, J., Aburto, M., Aizpiri, S., Chasco, L., & Quintana, J. M. (2020). Predictive factors over time of health-related quality of life in COPD patients. Respiratory research, 21(1), 138. https://doi.org/10.1186/S12931-020-01395-Z
dc.identifier.doi10.1186/S12931-020-01395-Z
dc.identifier.eissn1465-993X
dc.identifier.urihttps://hdl.handle.net/20.500.14454/2980
dc.language.isoeng
dc.publisherNLM (Medline)
dc.rights© The Author(s) 2020
dc.subject.otherPulmonary disease
dc.subject.otherChronic obstructive
dc.subject.otherPhysical activity
dc.subject.otherHospitalizations
dc.subject.otherQuality of life
dc.titlePredictive factors over time of health-related quality of life in COPD patientsen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.issue1
oaire.citation.titleRespiratory research
oaire.citation.volume21
oaire.licenseConditionhttps://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
Archivos
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
esteban_predictive_2020.pdf
Tamaño:
864.58 KB
Formato:
Adobe Portable Document Format
Descargar
Colecciones
Artículos