Exploring the interrelations of obsessions, compulsions, and health: the mediating role of psychotic symptoms in individuals with obsessive-compulsive disorder

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dc.contributor.authorAonso Diego, Gema
dc.contributor.authorParada Fernández, Pamela
dc.contributor.authorMendo Sancho, Laura
dc.contributor.authorMacía Guerrero, Laura
dc.contributor.authorEstévez Gutiérrez, Ana
dc.contributor.authorMaruottolo, Claudio
dc.date.accessioned2025-11-07T09:15:11Z
dc.date.available2025-11-07T09:15:11Z
dc.date.issued2025-09-17
dc.date.updated2025-11-07T09:15:11Z
dc.description.abstractBackground: Despite the high comorbidity between obsessive-compulsive and psychotic symptoms, little is known about its impact on the health of individuals with obsessive-compulsive disorder (OCD). This study aimed to 1) explore the prevalence of psychotic symptoms in individuals with OCD, and 2) examine the mediating role of psychotic symptoms in the relationship between obsessive-compulsive symptoms and overall health. Methods: This study included 102 participants undergoing treatment for OCD (Mage = 42.33, SD = 14.40, 52.9 % female). Structural equation modeling was employed to assess whether psychotic symptoms mediated the relationship between obsessive-compulsive symptoms and health outcomes. Results: Among participants with OCD (from mild to severe), 53.9 % exhibited positive psychotic symptoms, 74.7 % presented negative psychotic symptoms, and 83.5 % showed depressive psychotic symptoms. A significant correlation was found between OCD symptoms and psychotic symptoms (r ranging from .338 to .512). Structural equation modeling indicated that psychotic symptoms fully mediated the relationship between compulsions and health. Conclusions: Understanding the intricate relationship between OCD and psychotic symptoms remains a critical challenge in mental health research and clinical practice. Enhanced insights into this connection could facilitate more precise diagnoses and allow for more personalized treatments.en
dc.description.sponsorshipFunding for this study was provided by the Directorate General for the Regulation of Gambling (ref.: SUBV24/00009) and by a Postdoctoral grant from Ministry of Science (MCIN/AEI/10.13039/501100011033) and from European Union NextGenerationEU/PRTR (ref.: JDC2022- 048311-I)en
dc.identifier.citationAonso-Diego, G., Parada-Fernández, P., Mendo, L., Macía, L., Estévez, A., & Maruottolo, C. (2025). Exploring the interrelations of obsessions, compulsions, and health: the mediating role of psychotic symptoms in individuals with obsessive-compulsive disorder. Journal of Psychiatric Research, 191, 54-61. https://doi.org/10.1016/J.JPSYCHIRES.2025.09.022
dc.identifier.doi10.1016/J.JPSYCHIRES.2025.09.022
dc.identifier.eissn1879-1379
dc.identifier.issn0022-3956
dc.identifier.urihttps://hdl.handle.net/20.500.14454/4310
dc.language.isoeng
dc.publisherElsevier Ltd
dc.rights© 2025 The Authors
dc.subject.otherComorbidity
dc.subject.otherHealth
dc.subject.otherNegative symptoms
dc.subject.otherObsessive-compulsive disorder
dc.subject.otherPositive symptoms
dc.subject.otherPsychotic symptoms
dc.titleExploring the interrelations of obsessions, compulsions, and health: the mediating role of psychotic symptoms in individuals with obsessive-compulsive disorderen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.endPage61
oaire.citation.startPage54
oaire.citation.titleJournal of Psychiatric Research
oaire.citation.volume191
oaire.licenseConditionhttps://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
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