Cognitive scores as a potential diagnostic tool in schizophrenia: the use of raw and discrepancy scores

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dc.contributor.authorGómez Gastiasoro, Ainara
dc.contributor.authorPeña Lasa, Javier
dc.contributor.authorZubiaurre Elorza, Leire
dc.contributor.authorPino, Rocío del
dc.contributor.authorIbarretxe Bilbao, Naroa
dc.contributor.authorOjeda del Pozo, Natalia
dc.date.accessioned2025-08-28T09:49:59Z
dc.date.available2025-08-28T09:49:59Z
dc.date.issued2020-11-09
dc.date.updated2025-08-28T09:49:59Z
dc.description.abstractObjective: Cognitive scores could be a useful tool when discriminating between patients with schizophrenia (SZ) and non-psychiatric population. However, whether these scores can contribute to the accurate diagnosis of the disease is still unclear. Therefore, this study aimed to identify the best approach as to the inclusion of cognitive impairment as a potential clinical tool in the diagnosis of SZ. Method: A total of 258 patients with SZ and 202 healthy controls (HC) were assessed by means of the Hopkins Verbal Learning Test-Revised (HVLT-R) and the Trail Making Test-A (TMT-A). In addition to raw scores, participants' discrepancy scores (DS) in these two cognitive measures were calculated using regression-based norms controlling for age, years of education and premorbid intelligence quotient. Receiver-operating characteristic analyses were performed for both scores in order to assess their diagnostic properties. Results: The areas under the curve (AUC) of the HVLT-R total and delayed recall, and TMT-A raw scores were statistically significant and ranged from 0.67 to 0.87. Although significant, AUC of verbal memory DS were lower than those of raw scores (AUC = 0.84; AUC = 0.80). AUC of TMT-A DS was not significant. Conclusions: Results suggest that cognitive scores are useful and accurate when discriminating and classifying patients with SZ and HC in the present sample. Raw scores were shown to be more accurate than DS in patients with SZ and to present good diagnostic properties especially regarding verbal memory measures. Obtained indices support the use of cognitive scores as diagnostic criterion in the diagnosis of SZ.en
dc.description.sponsorshipBasic and Applied Investigation Project of the Basque Government, Grant/Award Number: PI_2014_1_43; Department of Education, Linguistic Politics and Culture of the Basque Government, Grant/Award Number: PRE_2015_1_0444; Department of Health of the Basque Government, Grant/Award Number: 2011111102en
dc.identifier.citationGómez-Gastiasoro, A., Peña, J., Zubiaurre-Elorza, L., del Pino, R., Ibarretxe-Bilbao, N., & Ojeda, N. (2020). Cognitive scores as a potential diagnostic tool in schizophrenia: the use of raw and discrepancy scores. Clinical Psychologist, 24(1), 73-81. https://doi.org/10.1111/CP.12191
dc.identifier.doi10.1111/CP.12191
dc.identifier.eissn1742-9552
dc.identifier.issn1328-4207
dc.identifier.urihttps://hdl.handle.net/20.500.14454/3418
dc.language.isoeng
dc.publisherWiley-Blackwell Publishing Ltd
dc.rights© 2019 The Authors
dc.subject.otherAssessment
dc.subject.otherCognition
dc.subject.otherDiscrepancy scores
dc.subject.otherProcessing speed
dc.subject.otherSchizophrenia
dc.subject.otherVerbal memory
dc.titleCognitive scores as a potential diagnostic tool in schizophrenia: the use of raw and discrepancy scoresen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.endPage81
oaire.citation.issue1
oaire.citation.startPage73
oaire.citation.titleClinical Psychologist
oaire.citation.volume24
oaire.licenseConditionhttps://creativecommons.org/licenses/by-nc-nd/4.0/
oaire.versionVoR
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