Combining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trial

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dc.contributor.authorPeña Lasa, Javier
dc.contributor.authorIbarretxe Bilbao, Naroa
dc.contributor.authorSánchez Gómez, Pedro Manuel
dc.contributor.authorIriarte Durán, María B.
dc.contributor.authorElizagarate Zabala, Edorta
dc.contributor.authorGaray, María A.
dc.contributor.authorGutiérrez, Manuel
dc.contributor.authorIribarren, Aránzazu
dc.contributor.authorOjeda del Pozo, Natalia
dc.date.accessioned2026-02-02T16:12:00Z
dc.date.available2026-02-02T16:12:00Z
dc.date.issued2016-11-09
dc.date.updated2026-02-02T16:12:00Z
dc.description.abstractThis study examined the efficacy of an integrative cognitive remediation program (REHACOP) in improving cognition and functional outcome in patients with schizophrenia. The program combines cognitive remediation, social cognitive intervention, and functional skills training. Few studies have attempted this approach. One hundred and eleven patients diagnosed with schizophrenia were randomly assigned to either the cognitive remediation group (REHACOP) or an active control group (occupational activities) for 4 months (three sessions per week, 90 min). Primary outcomes were change on general neurocognitive performance and social cognition, including theory of mind (ToM), emotion perception (EP), attributional style, and social perception (SP). Secondary outcomes included changes on clinical symptoms (Positive and Negative Syndrome Scale) and functional outcome (UCSD Performance-Based Skills Assessment and the Global Assessment of Functioning). The trial was registered with clinicaltrials.gov (NCT02796417). No baseline group differences were found. Significant differences were found in the mean change between the REHACOP group and control group in neurocognition (•p2=0.138), SP (•p2=0.082), ToM (•p2=0.148), EP (•p2=0.071), negative symptoms (η•p2=0.082), emotional distress (η•p2=0.136), Global Assessment of Functioning (η•p2=0.081), and UCSD Performance-Based Skills Assessment (η•p2=0.154). The combination of cognitive remediation, social cognitive intervention, and functional skills training demonstrated statistically significant and clinically meaningful changes in neurocognition, social cognition, negative, and functional disability.en
dc.description.sponsorshipThis study was supported by the Department of Health of the Basque Government (2011111102 to Dr Natalia Ojeda) and BFI-2010-407.en
dc.identifier.citationPeña, J., Ibarretxe-Bilbao, N., Sánchez, P., Iriarte, M. B., Elizagarate, E., Garay, M. A., Gutiérrez, M., Iribarren, A., & Ojeda, N. (2016). Combining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trial. npj Schizophrenia, 2. https://doi.org/10.1038/NPJSCHZ.2016.37
dc.identifier.doi10.1038/NPJSCHZ.2016.37
dc.identifier.eissn2334-265X
dc.identifier.urihttps://hdl.handle.net/20.500.14454/4964
dc.language.isoeng
dc.publisherNature Publishing Group
dc.rights© The Author(s) 2016
dc.titleCombining social cognitive treatment, cognitive remediation, and functional skills training in schizophrenia: a randomized controlled trialen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.titlenpj Schizophrenia
oaire.citation.volume2
oaire.licenseConditionhttps://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
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