Influence of rGO on the crystallization kinetics, cytoxicity, and electrical and mechanical properties of poly (L-lactide-co-ε-caprolactone) scaffolds

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dc.contributor.authorDíaz Tajada, Esperanza
dc.contributor.authorLeón Díaz, Joseba
dc.contributor.authorMurillo Marrodán, Alberto
dc.contributor.authorRibeiro, Sylvie
dc.contributor.authorLanceros Méndez, Senén
dc.date.accessioned2025-09-03T10:45:04Z
dc.date.available2025-09-03T10:45:04Z
dc.date.issued2022-10-23
dc.date.updated2025-09-03T10:45:04Z
dc.description.abstractBiodegradable scaffolds of poly (L-lactide-co-ε-caprolactone) (PLCL) and reduced graphene oxide (rGO) were prepared by TIPS (thermally induced phase separation). The nonisothermal cold crystallization kinetics were investigated by differential scanning calorimetry (DSC) with various cooling rates. The experimental values indicate that nonisothermal crystallization improves with cooling rate, but the increasing rGO concentration delays crystallization at higher temperatures. The activation energies were calculated by the Kissinger equation; the values were very similar for PLCL and for its compounds with rGO. The electrical conductivity measurements show that the addition of rGO leads to a rapid transition from insulating to conductive scaffolds with a percolation value of ≈0.4 w/w. Mechanical compression tests show that the addition of rGO improves the mechanical properties of porous substrates. In addition, it is an anisotropic material, especially at compositions of 1% w/w of rGO. All of the samples with different rGO content up to 1% are cytotoxic for C2C12 myoblast cells.en
dc.description.sponsorshipUniversity of The Basque Center; Spanish State Research Agency (AEI) and the European Regional Development Fund (ERFD) through the project PID2019-106099RB-C43/AEI/10.13039/501100011033 and from the Basque Government Industry Departments under the ELKARTEK program; also supported by FCT–Fundação para a Ciência e Tecnologia (FCT) under the scope of the strategic funding of UID/FIS/04650/2020 and UIDB/04469/2020 units and project PTDC/BTM-MAT/28237/2017en
dc.identifier.citationDíaz, E., León, J., Murillo-Marrodán, A., Ribeiro, S., & Lanceros-Méndez, S. (2022). Influence of rGO on the crystallization kinetics, cytoxicity, and electrical and mechanical properties of poly (L-lactide-co-ε-caprolactone) scaffolds. Materials, 15(21). https://doi.org/10.3390/MA15217436
dc.identifier.doi10.3390/MA15217436
dc.identifier.eissn1996-1944
dc.identifier.urihttps://hdl.handle.net/20.500.14454/3473
dc.language.isoeng
dc.publisherMDPI
dc.rights© 2022 by the authors
dc.subject.otherCrystallization
dc.subject.otherCytotoxicity
dc.subject.otherElectrical properties
dc.subject.otherMechanical properties
dc.subject.otherPLCL/rGO
dc.subject.otherScaffolds
dc.titleInfluence of rGO on the crystallization kinetics, cytoxicity, and electrical and mechanical properties of poly (L-lactide-co-ε-caprolactone) scaffoldsen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.issue21
oaire.citation.titleMaterials
oaire.citation.volume15
oaire.licenseConditionhttps://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
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