Predictive value of body composition and core symptoms in schizophrenia for cardiorespiratory fitness: CORTEX-SP study

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dc.contributor.authorTous Espelosín, Mikel
dc.contributor.authorIriarte Yoller, Nagore
dc.contributor.authorPavón Navajas, Cristóbal
dc.contributor.authorSánchez Gómez, Pedro Manuel
dc.contributor.authorSampedro, Agurne
dc.contributor.authorMaldonado Martín, Sara
dc.date.accessioned2026-01-23T12:59:35Z
dc.date.available2026-01-23T12:59:35Z
dc.date.issued2022-09-01
dc.date.updated2026-01-23T12:59:35Z
dc.description.abstractCardiorespiratory fitness (CRF) can be directly measured and assessed by the cardiopulmonary exercise test (CPET) or estimated from different field tests as the Modified Shuttle Walking Test (MSWT). The CRF in schizophrenia (SP) population may be altered due to sex, age, body composition and core symptoms variables. However, the extent to which each domain influences CRF in this pathology is still unknown. To analyze the predictive value of body composition and core symptoms in SP for CRF. Participants (N = 144, 41.7 ± 10.3 yr old) with SP were assessed with (1) body mass index and fat percentage; (2) upright bicycle ergometer using an incremental ramp protocol and the MSWT; and (3) positive and negative symptoms of the disease [“Positive and Negative Syndrome Scale” (PANSS) and “The Brief Negative Symptom Scale” (BNSS)]. In the Stepwise Multiple Regression analyses, those variables which correlated (Spearman’s Rho) significantly with each CFR scores were included. Lower negative symptoms (P<0.001) and positive PANSS (P=0.035) predicted V̇O2peak (L·min−1) (R2=28.3%). Lower negative symptoms (P<0.001), positive PANSS (P=0.006) and fat body mass (P<0.001) explained V̇O2peak (mL·kg−1·min−1) (R2=46.5%). MSWT was predicted (R2=58.9%) by lower negative symptoms (P=0.001), body mass (P<0.001) and total PANSS (P=0.004). In patients with SP significantly higher CRF was detected in those with lower negative and positive symptoms, as well as lower body mass. Exercise interventions for improving CRF should be promoting in this population for a better control of core symptoms.en
dc.identifier.citationTous-Espelosin, M., Iriarte Yoller, N., Pavón Navajas, C., Sanchez, P. M., Sampedro, A., & Maldonado-Martín, S. (2022). Predictive value of body composition and core symptoms in schizophrenia for cardiorespiratory fitness: CORTEX-SP study. European Psychiatry, 65(S1), S195-S196. https://doi.org/10.1192/J.EURPSY.2022.514
dc.identifier.doi10.1192/J.EURPSY.2022.514
dc.identifier.eissn1778-3585
dc.identifier.issn0924-9338
dc.identifier.urihttps://hdl.handle.net/20.500.14454/4841
dc.language.isoeng
dc.publisherCambridge University Press
dc.rights© Cambridge University Press 2026
dc.subject.otherCardiorespiratory fitness
dc.subject.otherBody composition
dc.subject.otherCore symptoms
dc.subject.otherSchizophrénia
dc.titlePredictive value of body composition and core symptoms in schizophrenia for cardiorespiratory fitness: CORTEX-SP studyen
dc.typejournal article
oaire.citation.endPageS196
oaire.citation.issueS1
oaire.citation.startPageS195
oaire.citation.titleEuropean Psychiatry
oaire.citation.volume65
oaire.licenseConditionhttp://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
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