Examinando por Autor "Mazzucco, Guillermo"

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    Evidence-based practice in respiratory healthcare professionals in Latin America: a survey of the Latin American Thoracic Association (ALAT)
    (Facultad de Salud de la Universidad del Valle, 2024) Benavides, Vicente; Torres Castro, Rodrigo; Fregonezi, Guilherme A.F.; Resqueti, Vanessa; Pérez Nieto, Orlando; Cañas, Alejandra; Larrateguy, Santiago; Mazzucco, Guillermo; Betancourt Peña, Jhonatan
    Background: Evidence-based practice (EBP) is a systematic approach to professional practice using the best available evidence to make informed clinical decisions in healthcare. It is necessary to measure and identify strengths and opportunities for improvement. Objective: To assess the knowledge and application of EBP in respiratory health professionals in Latin America. Methods: A cross-sectional study was conducted. The questionnaire was distributed online to health professionals in Latin American countries. Demographic data, professional characteristics, EBP training, and questionnaire responses were collected. Descriptive and inferential statistical analyses were performed. Results: A total of 448 respiratory health professionals participated in the study. Responses were obtained from 17 countries where the majority were female, with an average age of 42. Participants included physicians, physiotherapists, nurses, respiratory therapists, speech therapists, and occupational therapists. Overall scores indicated moderate to high levels of EBP knowledge and application. However, variations were observed in different dimensions. Factors such as EBP training, reading scientific articles, and professional characteristics were associated with higher scores. Barriers to implementing EBP were identified mostly related to institutional support. Conclusions: This study provides information on the knowledge and implementation of EBP in respiratory health professionals in Latin America. Although the overall levels of knowledge and application of EBP were moderate to high, there are options for improvement, especially in addressing barriers to implementation.
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    Is non-invasive ventilation effective in improving the exercise capacity in patients with cardiac heart failure?: a randomised crossover trial
    (Public Library of Science, 2025-07-01) Mazzucco, Guillermo; Torres Castro, Rodrigo; Intelangelo, Leonardo; Lista Paz, Ana; Escalante, Juan Pablo; Zumeta Olaskoaga, Lore; Veiga, Gonzalo; Arbillaga Etxarri, Ane
    Introduction Heart failure (HF) is a prevalent global health issue, characterized by the heart’s inability to effectively pump or fill with blood, leading to inadequate cardiac output. Despite advances in medical treatments, exercise intolerance remains a significant challenge, impacting their quality of life and contributing to frequent hospitalizations. Recent studies suggest that non-invasive ventilation (NIV) may further enhance exercise performance by reducing ventilatory workload and fatigue. However, limited research has directly compared different ventilatory modes during exercise in patients with heart failure. This study aims to evaluate the effects of two NIV devices on exercise capacity. Methods A randomised crossover trial was conducted in patients with HF, reduced ejection fraction (≤ 40%), New York Heart Association functional class I-III and clinically stable. All participants underwent an initial assessment followed by an incremental exercise test to determine maximum aerobic velocity. They were then randomized to perform three constant work rate tests on separate days under three conditions: (1) with Continuous Positive Airway Pressure (CPAP), (2) with pressure support (PS) and (3) without NIV. The primary outcome was time to exhaustion. Key physiological variables were recorded during each test. Participants were recruited and completed all testing between April 29 and July 18, 2022. ClinicalTrials.gov registration number: NCT05433610. Results A total of 11 patients (mean age: 67±9.6 years) completed the study. Exercise duration was significantly longer in the pressure support group (9.8±6.2 minutes) compared to the CPAP group (8.9±6.0 minutes) and the control group (7.3±6.2 minutes) (p=0.043). No significant differences were found in average heart rate (HR), final HR, or oxygen saturation (SpO2) between the groups (p>0.05). Similarly, dyspnea and leg fatigue (modified Borg scale) showed no statistically significant differences between conditions (p>0.05). Conclusion The use of NIV, particularly the PS mode, during exercise significantly improved exercise duration in patients with HF compared to CPAP or no ventilatory support.