Examinando por Autor "Amor Barbosa, Marta"

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    Reference equations for maximal respiratory pressures in healthy children and adolescents
    (Sociedad Espanola de Neumologia y Cirugia Toracica (SEPAR), 2025-09-22) Barral Fernández, Margarita; Jácome Pumar, María Amalia; Souto-Camba, Sonia; González Doniz, Luz; Ramón Belmonte, María Antonia; Amor Barbosa, Marta; Arbillaga Etxarri, Ane; Mazzucco, Guillermo; Bravo Cortés, Pilar; Corral Núñez-Flores, Tamara del; Martín Valero, Rocío; Llorca Cerdà, Carlos; Murcia Lillo, Fabiola; Sanchez Santos, José Antonio; Francín Gallego, Marina; Martín Cortijo, Concepción; García Delgado, Esther; Serrano Veguillas, Cristina; Varas de la Fuente, Ana B.; San José Herranz, Paula; González Montañez, Carolina; Gimeno Santos, Elena; Torres Castro, Rodrigo; Fregonezi, Guilherme A.F.; Pardàs Peraferrer, Mireia; Vilaró, Jordi; Fernández Cadenas, Ángeles; Ríos Cortés, Antonio Tomás; Moreno Valera, María José; Langer, Daniel; Lista Paz, Ana
    Objectives: Maximal respiratory pressures are key indicators of respiratory muscle strength; however, reference equations and cut-offs to define respiratory muscle weakness are scarce in the European paediatric population. The aim was to create sex-specific reference equations for maximal inspiratory and expiratory pressures (PImax/PEmax) in a large sample of healthy children and to objectively establish cut-offs to define respiratory muscle weakness. Methods: A multicentre cross-sectional study was conducted across 14 Spanish centres. Healthy children aged 6–18 years, stratified by sex and age, were recruited. Maximal respiratory pressures were measured following standardized methodology in accordance with international guidelines. Reference equations were developed through multiple linear regression analyses. Age- and sex specific cut-offs for respiratory muscle weakness were determined using Z-scores ≥ 1.645 standard deviation (SD) below group means. Results: The final sample included 513 subjects (257 boys; 11.5 [SD3.5] years). Reference equations are: (1) PImax: boys = −41.41 + 10.21 * age + 6.26 * body mass index (BMI) − 0.37 * age * BMI; girls = 125.96–0.34 * age − 0.41 * age2 − 5.75 * BMI + 0.63 * age * BMI; (2) PEmax: boys = 20.93 + 5.23 * age + 2.93 * BMI; girls = −12.67 + 11.98 * age − 0.39 * age2 + 2.57 * BMI. Cut-offs for respiratory muscle weakness are higher in boys and increase with age (p < .001). Depending on age, PImax cut-offs range from 46 to 85 cmH2O in boys and from 45 to 68 cmH2O in girls, while PEmax cut-offs span 54–98 cmH2O in boys and 57–85 cmH2O in girls. Conclusions: This study provides new reference equations for PImax and PEmax derived from the largest dataset of normative values in European children and adolescents. It also establishes age-specific cut-offs to define respiratory muscle weakness. These findings will facilitate the identification of respiratory muscle weakness and the selection of candidates for targeted training programmes.