Examinando por Autor "Aburto Barrenechea, Myriam"

Mostrando 1 - 2 de 2
  • Miniatura
    Ítem
    Impact of changes in physical activity on health-related quality of life among patients with COPD
    (European Respiratory Society, 2010-07-31) Esteban González, Cristóbal; Quintana López, José María; Aburto Barrenechea, Myriam; Moraza Cortés, Javier; Egurrola Izquierdo, Mikel; Pérez Izquierdo, Julio; Aizpiri Rivero, Susana; Aguirre Larracoechea, Urko; Capelastegui, Alberto
    The aim of this study was to evaluate whether changes in regular physical activity (PA) affect health-related quality of life (HRQoL) among patients with chronic obstructive pulmonary disease (COPD). 611 patients (mean age 67.2¡8.4 yrs; forced expiratory volume in 1 s 49.7¡14.6) completed the St George’s Respiratory Questionnaire (SGRQ), the Chronic Respiratory Questionnaire (CRQ) and the Medical Outcomes Short Form (SF-36) questionnaire. PA, defined as patients’ selfreported regular walking times, was classified as low, moderate and high. After 5 yrs, 391 survivors completed these instruments again. After adjustment for relevant confounders, patients who reported low PA at baseline and who increased their PA over the study period improved their SGRQ and CRQ scores by 15.9 and 8.7 points, respectively. Patients who moved from moderate to high PA improved their SGRQ scores by 18.4 and their CRQ scores by 14.8. Slightly smaller increases were observed for patients who maintained a high level of PA throughout the study period. Maintaining a low level of PA or decreasing PA over the study period was associated with a significant HRQoL decline. Among COPD patients, a reduction in time spent engaging in PA or maintaining a low level may impair HRQoL, whereas an increase in PA can improve HRQoL parameters.
  • Miniatura
    Ítem
    Predictive factors over time of health-related quality of life in COPD patients
    (NLM (Medline), 2020-06-05) Esteban González, Cristóbal; Arostegui Madariaga, Inmaculada; Aramburu Ojembarrena, Amaia; Moraza, Javier; Nájera Zuloaga, Josu; Aburto Barrenechea, Myriam; Aizpiri Rivero, Susana; Chasco, Leyre; Quintana, José María
    BACKGROUND: Health-related quality of life (HRQoL) should be seen as a tool that provides an overall view of the general clinical condition of a COPD patient. The aims of this study were to identify variables associated with HRQoL and whether they continue to have an influence in the medium term, during follow-up. METHODS: Overall, 543 patients with COPD were included in this prospective observational longitudinal study. At all four visits during a 5-year follow-up, the patients completed the Saint George's Respiratory Questionnaire (SGRQ), pulmonary function tests, the 6-min walk test (6MWT), and a physical activity (PA) questionnaire, among others measurements. Data on hospitalization for COPD exacerbations and comorbidities were retrieved from the personal electronic clinical record of each patient at every visit. RESULTS: The best fit to the data of the cohort was obtained with a beta-binomial distribution. The following variables were related over time to SGRQ components: age, inhaled medication, smoking habit, forced expiratory volume in one second, handgrip strength, 6MWT distance, body mass index, residual volume, diffusing capacity of the lung for carbon monoxide, PA (depending on level, 13 to 35% better HRQoL, in activity and impacts components), and hospitalizations (5 to 45% poorer HRQoL, depending on the component). CONCLUSIONS: Among COPD patients, HRQoL was associated with the same variables throughout the study period (5-year follow-up), and the variables with the strongest influence were PA and hospitalizations.